Dental caries and bacterial load in saliva and dental biofilm of type 1 diabetics on continuous subcutaneous insulin infusion

Abstract Objectives Since most of the studies evaluates diabetics on multiple daily injections therapy and continuous subcutaneous insulin infusion may help gain better metabolic control and prevent complications, the objective of this study was to evaluate the prevalence of dental caries, the unstimulated salivary flow rate and the total bacteria load, Streptococcus spp. levels and Lactobacillus spp. levels in saliva and supragingival dental biofilm of type 1 diabetics on insulin pump. Material and Methods Sixty patients with type 1 diabetes on insulin pump and 60 nondiabetic individuals were included. The dental caries evaluation was performed using ICDAS and the oral hygiene was assessed according to Greene and Vermillion Simplified Oral Hygiene Index. Unstimulated saliva and supragingival dental biofilm were collected. Total bacteria, Streptococcus spp. and Lactobacillus spp. was quantified by qPCR. Results Patients with type 1 diabetes had a higher prevalence of dental caries and filled and missing teeth when compared with the control group. These patients were associated with more risk factors for the development of dental caries, namely a lower unstimulated salivary flow rate and a higher bacterial load in saliva and dental biofilm. Conclusion Some risk factors related to dental caries were associated with type 1 diabetics. An early diagnosis combined with the evaluation of the risk profile of the diabetic patient is imperative, allowing the dental caries to be analyzed through a perspective of prevention and the patient to be integrated into an individualized oral health program.

Identificação das mudanças na mastigação e deglutição de indivíduos submetidos à glossectoma parcial / Identification of chewing and swallowing changes in individuals submitted to partial glossectomy

OBJETIVO: Identificar as alterações de mastigação e deglutição decorrentes da cirurgia curativa do câncer de língua, com extensão inferior a 50 por cento da dimensão da língua e sem comprometimento do soalho da boca e da base da língua. MÉTODOS: Foram realizadas avaliações das funções de mastigação e deglutição em nove pacientes, seis homens e três mulheres, no período pré-operatório, aplicando-se um protocolo específico. No pós-operatório mediato, três semanas após a cirurgia, cinco pacientes foram reavaliados, quatro homens e uma mulher, seguindo o mesmo protocolo. Para verificar a significância dos resultados foi utilizado o teste não paramétrico de Kruskall Wallis (Teste H). RESULTADOS: Comparando-se os achados do pré-operatório com os achados do pós-operatório encontramos, de forma significativa (p<0,05), mudança da via de alimentação, que passou de uma alimentação exclusivamente oral, para uma alimentação exclusivamente enteral. Também houve mudança significativa na eficiência mastigatória, que passou a ser ineficiente em todos os pacientes. Percebeu-se, de forma significativa, a dificuldade dos pacientes em manipular o bolo alimentar durante o processo de mastigação, gerando dificuldade na formação de um bolo coeso. Isso demonstra que a cirurgia influencia na realização desta função, ou seja, a perda de parte da língua compromete o processo de mastigação. A deglutição também foi prejudicada pela cirurgia, uma vez que o teste demonstrou de forma significativa a presença de estase oral, após a deglutição e movimentos compensatórios de cabeça para a deglutição de alimentos sólidos. CONCLUSÃO: Os pacientes submetidos à glossectomia parcial apresentam mudanças na mastigação e deglutição decorrentes do tratamento cirúrgico.

PURPOSE: To identify the commonest changes in chewing and swallowing as a result from curative tongue cancer surgery, with less than 50 percent of tongue resection and preservation of both mouth floor and tongue base. METHOSD: Nine patients - six men and three women - were assessed during the pre-surgical period, using a specific protocol. During the mediate postsurgical period, five patients - four men and one woman - were reassessed using the same protocol. The Kruskall Wallis non-parametric test (Test H) was used to analyze the significance of the results. RESULTS: The comparison between pre and postoperative results showed significant (p<0,05) changes from oral to enteral feeding. There was also a significant change in chewing efficiency, which became ineffective in all patients. It was significantly observed the patients' difficulty in handling the food bolus during the chewing process, causing difficulty in forming a cohesive bolus. This demonstrates that surgery influences this function, that is, the partial loss of the tongue undermines the chewing process. The swallowing process was also impaired by the surgery: the protocol demonstrated significant presence of oral stasis after swallowing, and compensatory head movements for swallowing solids. CONCLUSION: The patients submitted to partial glossectomy presented significant alterations in chewing and swallowing as a result from surgical cancer treatment.